The pE-10: Improving data quality and throughput
We’re delighted to announce the launch of the new pE-10, a 10-channel LED Illumination System developed for manufacturers of multiplex imaging platforms. Covering wavelengths from UV right up to 850 nm, the pE-10 enables high-plex fluorescence imaging at the hardware level, allowing OEMs to deliver robust, reproducible data for spatial biology applications, without reliance on complex post-processing.
LED Multiplexing for Spatial Biology and More
Fluorescence imaging systems for spatial biology demand higher plex counts with speed, reproducibility and quantitative confidence. While advances in image analysis often take centre stage, the optical foundation – specifically the illumination system and optical filters – are key in defining system performance and data validity across instruments, laboratories and timepoints.
Delivering Robust Data, Faster Than Ever
The arrival of the pE-10 brings simultaneous control of ten individual LEDs, boosting throughput by capturing multiple targets in a single acquisition.
When paired with the Kromnigon SpectraSplit® 10 optical filters, each LED is carefully tuned for superior spectral separation to deliver clean, high-quality images directly at acquisition – without reliance on complex spectral unmixing or ‘black-box’ algorithms.
Resolving signals in hardware provides confidence that data accurately represents the underlying biology, which is essential across spatial biology applications, from discovery through to translational studies and regulated clinical pathology.
“The pE-10 is a major step forward for next-generation high-plex spatial biology,” commented Dr. Jake Davies, MD at CoolLED.
“By combining the latest precision LED technology with hardware-based spectral separation of up to 10 fluorophores in a single acquisition, OEMs gain a competitive edge in a fast-moving market by providing scientists with the ability to generate reproducible data, faster.”
