News

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Advancing biomedical discovery with Fura-2 imaging

Two new Application Notes detail how Fura-2 imaging provides insights into the effects of air pollution, and mitochondrial function.

Interested in calcium imaging?

Join us at the Open Calcium Conference and find out more about Illumination Systems for Fura-2

George Chennell image

You’ve still got time to win a pE-300^ultra

Deadline extended until the end of July for our Image in an Image competition!

fens

Join us at FENS 2020

Involved in neuroscience? Drop by our virtual booth to find out how we can help.

NEW pE 100

pE-100 is now cooler than ever

Refreshed design of our single-wavelength pE-100 Illumination System

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Multi-channel fluorescence has never been so affordable

Transforming the Olympus CX43 microscope into a fluorescence imaging system with three independently controllable channels

CBBC

A window into the science business in China

Join us for the China-Britain Business Council session on Thursday 18^th June where we share our experience as a UK scientific business in China.

pE 300white in space 2

CoolLED Illumination Systems are out of this world!

Advancing life science research on the International Space Station (ISS) with the pE-300^white

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Free Andor conference

We might not be out & about at the moment, but you can still pop over to our booth at the free Andor Technology Cell & Developmental Biology Virtual Meeting in June!

pT 100 LLG

Expanding the popular pT-100 range

Enhancing electrophysiology with NEW transmitted LED illumination

Mental health montage for web

We’re taking mental health action

How we’ve been looking after ourselves and others during lockdown

Liz Stark

A CoolLED is for life…

Liz looks back at how far LED illumination has come in the last decade

Covid UN

Win £100 donation to COVID-19 Solidarity Response Fund

Share your application note and help in the fight against COVID-19!

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Under the Microscope #6: Investigating 280 nm LEDs in biomedical imaging

PhD student Mollie McFarlane explains her project developing the application of deep-UV LEDs.

All you need to know about our pE-300 Series

All you need to know about our pE-300 Series

How do the three systems differ? Do you need an SB or an MB model? And what are the benefits of direct fit versions? Take a look at our tutorial videos to find out everything you need to know!

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Happy Earth Day!

Take a moment to consider how we can take climate action together.

New white paper: How to boost irradiance

New white paper: How to boost irradiance

Learn how to configure your fluorescence microscope for bright, high-contrast images.

Aurox conference

Learn about LED illumination from the experts

A couple of ‘illuminating’ presentations from the Aurox virtual conference.

Medipan

Under the Microscope #5: The benefits of customisable LED Illumination Systems in automated imaging systems

In this issue, Dorian Sartorius from CoolLED’s long-standing OEM customer, Medipan, explains the importance of robust, customisable LED Illumination Systems in automated imaging systems.

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Boosting irradiance for Fura-2 on the Leica DMi8

Infinity port adaptor available for CoolLED pE-340^fura Illumination System

british science week

British Science Week

This week is British Science Week, and while every week is Science Week at CoolLED, we spoke to Helen from R&D to get a glimpse of what keeps our scientists & engineers busy at CoolLED!

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COVID-19: A message to our customers

Due to the recent changes to the COVID-19 situation, we are making some changes to ensure we keep our staff & customers safe, whilst continuing to provide customers with the best support. Our team is still contactable in a variety of ways, find out more here…

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Under the Microscope #4: Simultaneous in vivo fluorescence and DIC imaging of fast-moving samples

Laurent Gelman explains a clever technique for acquiring fluorescence and DIC images simultaneously in fast-moving samples.

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Well done to our Customer Service Team!

We received great feedback from a recent customer survey – thank you to everyone who responded.

#ThrowBackThursday – ASCB

We’re taking a look back at the ASCB conference where we talked to My Green Lab and Ludesco Microscopes to get their take on LED Illumination Systems in the lab.

International day of women and girls in science

Dr Isy Goodhand shares her views on women in the life sciences – there is a life outside of academia.

neuron

A controllable Illumination System for neuroscience discovery

Science snapshot: find out how the CoolLED pE-4000 is advancing neuroscience research in Hungary

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The Amora Explained

Have a look at our video to get an insight into our new OEM platform, the Amora

Win a pE-300<sup>ultra</sup>

Win a pE-300^ultra

Send us your “image in an image” to enter our competition with a difference!

UK Light Microscopy Facility Meeting 2020

We’re looking forward to sharing the latest developments in LED illumination technology plus the benefits of Sequence Runner in our talk on Monday at 14:15

CoolLED team raises over £100 for charity

CoolLED team raises over £100 for charity

CoolLED Christmas jumper day raises money for Save the Children

New Amora launched at ASCB

ASCB in Washington was a fantastic show, thanks to everyone who stopped by for a chat about our Illumination Systems and of course our New Amora OEM modular platform.

Under the Microscope #3: Simple LED Illumination System saves the day in Brazil

Tim Self explains how a CoolLED Illumination System saved the day in a collaborative project to reduce the use of antibiotics and fight antimicrobial resistance.

New Micro-Manager tutorial for pE-300 Series and pE-340fura

New Micro-Manager tutorial for pE-300 Series and pE-340fura

Are you using Micro-Manager with the CoolLED pE-300 Series or pE-340^fura? Find out how to configure your imaging software and set up an experiment in our new tutorial video.

Sowing the seeds for a brighter future

Sowing the seeds for a brighter future

A gift to everyone at CoolLED to celebrate our move to 26 Focus Way

New App Note: Improving microbiological testing in a diagnostic laboratory

New App Note: Improving microbiological testing in a diagnostic laboratory

Microbiology Laboratory Manager at Salisbury District Hospital, Collette Allen, described the benefits of LED Illumination Systems for microbe detection in a diagnostic laboratory.

Growth in LED illumination market drives CoolLED expansion

Growth in LED illumination market drives CoolLED expansion

A bigger, better premises on Focus Way for our growing business!

“Intensity” in a nutshell

“Intensity” in a nutshell

What does “illumination intensity” really mean and how do we measure it? We clear up the confusion and introduce an industry-standard approach in our new white paper.

Back to school

Back to school

We went along to John Hanson Community School to chat to school children about careers in STEM.

CoolLED welcomes Mike Foreman

CoolLED welcomes Mike Foreman

It is with great pleasure that CoolLED welcomes Mike Foreman to the Production Engineering team.

Under the Microscope #2: LED microscopy illumination in an academic imaging facility

Under the Microscope #2: LED microscopy illumination in an academic imaging facility

Find out why Imaging Facility Manager at the Kennedy Institute of Rheumatology, Dr Volodymyr Nechyporuk-Zloy, made the switch to CoolLED Illumination Systems.

Important information: update your address book

Important information: update your address book

New article published in Microscopy Today

New article published in Microscopy Today

Learn more about optimal LED filtering for fluorescence microscopy

Come along to our Macmillan coffee morning!

Come along to our Macmillan coffee morning!

Come along to our coffee morning Friday 27^th September from 10.30am and help us raise money for Macmillan Cancer Support.

Cai Clarke

CoolLED welcomes Cai Clarke

It is with great pleasure that CoolLED welcomes Cai Clarke to the Production Engineering team.

Welcome to our new website

Welcome to our new website

You will have noticed our website looks different, and here you can find out what’s new and improved.

Launching our new interview series

Launching our new interview series

Experts in the field explain how LED illumination systems are transforming fluorescence microscopy.

Supporting microscopists at Woods Hole

Supporting microscopists at Woods Hole

Read how we are supporting the Marine Biological Laboratory at Woods Hole, Massachusetts.

Higher irradiance, lower cost

Higher irradiance, lower cost

If you have a Leica DMi8 microscope, you can increase irradiance with a CoolLED Infinity Port adaptor for the pE-300 Series and pE-4000 Illumination Systems.

Liz Loseby

CoolLED welcomes Liz Loseby

It is with great pleasure that CoolLED welcomes Liz Loseby to the Production Team.

Work experience

Work experience

We welcomed Ethan Mayes to CoolLED for a week of work experience.

Teamwork makes the dream work!

Teamwork makes the dream work!

Teamwork is at the heart of CoolLED and drives us to provide the best service for our customers. We like to do things differently and this year’s away day featured a guest speaker, personality profiling… and inflatable pony racing.

Fundraising for the Air Ambulance

Fundraising for the Air Ambulance

We went along to the Hampshire and Isle of Wight Air Ambulance Air Base, understanding the incredible work they do and presenting our donation to the team.

Richard Coverdale wins the Nick Edwards Gold Award 2019

Richard Coverdale wins the Nick Edwards Gold Award 2019

We’re pleased to announce Richard Coverdale as this year’s winner of our Nick Edwards Gold Award (NEGA), in memory of our founder.

School’s Out!

School’s Out!

Students at Harrow Way School celebrated their Year 11 prom and we helped to make sure everyone could go along and celebrate with their classmates.

CoolLED welcomes Tom Shah for a summer internship.

CoolLED welcomes Tom Shah for a summer internship.

CoolLED welcomes Tom Shah back to the Marketing Team for an 8 week internship.

Ben Gee

CoolLED welcomes Benjamin Gee

It is with great pleasure that CoolLED welcomes Benjamin Gee to the Product Engineering team.

Western King

CoolLED welcomes Western King

It is with great pleasure that CoolLED welcomes Western King to the R&D team.

Helen Long

CoolLED welcomes Helen Long

It is with great pleasure that CoolLED welcomes Helen Long to the R&D team.

Students learn about the digital jobs of the future with CoolLED

Students learn about the digital jobs of the future with CoolLED

Over 300 students from 24 schools in North Hampshire came together to discover current and future digital careers in the technology industry from businesses themselves.

CoolLED welcomes Evie Cox

CoolLED welcomes Evie Cox

It is with great pleasure that CoolLED welcomes Evie Cox to the Production team.

CoolLED Recruitment

CoolLED is Recruiting in Production

CoolLED has an exciting opportunity for a Production Operative to join our Production Department.

Kieran Hotchkin

CoolLED welcomes Kieran Hotchkin

It is with great pleasure that CoolLED welcomes Kieran Hotchkin to the Production team.

Steve Cooper

CoolLED welcomes Stephen Cooper

It is with great pleasure that CoolLED welcomes Stephen Cooper to the Production team.

CoolLED welcomes Patrick De Guelle

CoolLED welcomes Patrick De Guelle

It is with great pleasure that CoolLED welcomes Patrick De Guelle to the Sales team.

CoolLED welcomes Carol Tindal

CoolLED welcomes Carol Tindal

It is with great pleasure that CoolLED welcomes Carol Tindal to the Admin team.

CoolLED announced as company of the year

CoolLED announced as company of the year

To top off another successful year, we’re proud to receive the Company of the Year Award from parent company, Judges Scientific.

CoolLED Recruitment

CoolLED is Recruiting in China

CoolLED is seeking to increase its sales resource by recruiting a China-based Field Sales Manager to continue the development of its business.

LED light for microscope

Benefits of Synchronising LED Illumination Systems to a Camera

Our very own Lynsey Burton reviews the benefits…

CoolLED Recruitment

CoolLED is Recruiting in Production Engineering

Due to strong growth in its core market and opportunities to expand CoolLED is looking to strengthen the team with a Technical Process Engineer (Production) and a Mechanical Design CAD Engineer (Production).

CoolLED Recruitment

CoolLED is Recruiting for three new roles

Due to strong growth in its core market and opportunities to expand CoolLED is looking to strengthen the team with a Production Engineering Manager, a Mechanical Design Engineer & an Embedded Systems Engineer.

CoolLED welcomes Jo Whetstone

CoolLED welcomes Jo Whetstone

It is with great pleasure that CoolLED welcomes Jo Whetstone to the Sales team.

CoolLED welcomes Isabel Goodhand

CoolLED welcomes Isabel Goodhand

It is with great pleasure that CoolLED welcomes Isabel Goodhand to the Marketing team.

Leg waxing and cakes for Red Nose Day 2019

Leg waxing and cakes for Red Nose Day 2019

Red Nose Day 2019 was a big success at CoolLED

Are you Using the Best Filter Sets for LED Fluorescence?

Are you Using the Best Filter Sets for LED Fluorescence?

CoolLED’s Danielle Love reviews the impact of LEDs on fluorescence imaging and considers the various benefits of optimal LED filtering.

CoolLED Recruitment

CoolLED is Recruiting in the Sales Team

CoolLED is seeking to increase its sales resource by recruiting a Field Sales Manager for Western USA to continue the development of its business in this area.

CoolLED Recruitment

CoolLED is Recruiting for an Administration Assistant

CoolLED is seeking an Administration Assistant to support the Operations Team and Administration Department.

CoolLED welcomes Lauren McQueen

CoolLED welcomes Lauren McQueen

It is with great pleasure that CoolLED welcomes Lauren McQueen to the Production team.

CoolLED welcomes Sandra Olufsen

CoolLED welcomes Sandra Olufsen

It is with great pleasure that CoolLED welcomes Sandra Olufsen to the Marketing team.

Proud to be Collaborating with The University of Strathclyde…

Proud to be Collaborating with The University of Strathclyde…

CoolLED is very proud to be collaborating with the University of Strathclyde once more. We’re excited to announce that Mollie McFarlane will be working with us on a new research project.

CoolLED Recruitment

CoolLED is Recruiting for a Field Sales Manager

CoolLED is seeking to increase its sales resource by recruiting a Field Sales Manager to continue the development of its business.

CoolLED welcomes Dinos Eleftheriadis

CoolLED welcomes Dinos Eleftheriadis

It is with great pleasure that CoolLED welcomes Dinos Eleftheriadis to the R&D team.

A Few Steps for CoolLED is a Continuous Gallop for Minstrel

A Few Steps for CoolLED is a Continuous Gallop for Minstrel

CoolLED were extremely proud to present a £1500 cheque to the RDA Andover earlier this week. We also got the chance to meet the lovely “Minstrel”, the horse we are now sponsoring for 2 years as a result of our fundraising efforts.

And the Careers Fair Quiz Winners Are…

And the Careers Fair Quiz Winners Are…

CoolLED present the worthy quiz winners with their prize!

CoolLED’s NEW pT-100 – launching December 2018

CoolLED’s NEW pT-100 – launching December 2018

Utilising the highly successful pE-100wht technology, we have further developed our LED solutions for Transmitted Light Applications. The pT-100 launches in December 2018.

CoolLED welcomes Tim Sulman

CoolLED welcomes Tim Sulman

It is with great pleasure that CoolLED welcomes Tim Sulman to the team. Tim will be responsible for Product Development within the R & D department.

CoolLED Recruitment

CoolLED is Recruiting for a Technical Content Specialist

Due to strong growth in its core market and opportunities to expand CoolLED is looking to strengthen its Marketing department with a Technical Content Specialist.

CoolLED Recruitment

CoolLED is Recruiting for a Production Operative

CoolLED has an exciting opportunity for a Production Operative to join our Production Department.

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

The C9orf72 protein interacts with Rab1a and the ULK1 complex to regulate initiation of autophagy

This is a very interesting paper that uses LED illumination in all the fluorescence microscopy.

Magictree at 70th Korean Physiology Society Meeting

Magictree at 70th Korean Physiology Society Meeting

Great to see our friends at Magictree exhibiting CoolLED’s pE-340fura for ratiometric Calcium Imaging

CoolLED Recruitment

CoolLED is Recruiting in Marketing

CoolLED has an exciting opportunity for an Events & Database Co-Ordinator to join the Marketing team

CoolLED did it!!! We Walked the Testway!

CoolLED did it!!! We Walked the Testway!

We did it!! A very wet and miserable day it may have been, but the CoolLED Team pushed through on Sunday 14th October to complete varying distances from 5-25.5 miles for a great cause.

Switch OFF Mercury Bulbs and Switch ON and Award Winning LED System

Switch OFF Mercury Bulbs and Switch ON and Award Winning LED System

With the instant on-off feature unique to LED systems, you can have the light you need and only when you need it.

Wave Goodbye to Mercury with CoolLED!

Wave Goodbye to Mercury with CoolLED!

The toxic effects of mercury have been well documented for decades, why on earth would you want to use it if there’s a more cost-effective, safer alternative with enhanced performance??

Alzheimer’s Society Coffee Morning

Alzheimer’s Society Coffee Morning

CoolLED would like to thank everyone who contributed towards our annual coffee morning last week.

pE-300 Series Secures ACT Label Status

CoolLED is delighted to announce that it’s pE-300 Series has been awarded the ACT Label for sustainability.

And The Nick Edwards Gold Award 2018 goes to…

And The Nick Edwards Gold Award 2018 goes to…

Huge congratulations to our 2018 Nick Edwards Gold Award Winner…

Manuel Beynon, Distributor+ at Bristol University

Manuel Beynon, Distributor+ at Bristol University

Great to see our CoolLED Distributor+ Manuel Beynon from Microscopes South West representing us at The Technical Conference at Bristol University last week.

Imaging & Microscopy publish Programmable LEDs Benefit Cell Viability

Imaging & Microscopy publish Programmable LEDs Benefit Cell Viability

CoolLED have a great article published in Imaging & Microscopy June 2018 –

European Placement Network brings Louis Burgy to CoolLED

European Placement Network brings Louis Burgy to CoolLED

We are proud to welcome Louis Burgy, a Swiss student studying Mechanical Engineering and Production Management.

CoolLED welcomes Tom Shah

CoolLED welcomes Tom Shah

CoolLED is pleased to welcome Tom Shah to the team for a 4-week internship.

CoolLED is Walking the Testway and needs your help!

CoolLED is Walking the Testway and needs your help!

This year CoolLED is taking part in the “Walk the Testway” event to raise money for the Andover Riding for the Disabled charity. Employees will be walking varying distances from 5 – 25 miles!

Fond Farewell to Phil

Fond Farewell to Phil

The time has come to bid farewell to Phil Joyce, our Production Engineer who is retiring.

Work Experience at CoolLED for George Dahne

Work Experience at CoolLED for George Dahne

CoolLED was proud to welcome George Dahne on work experience recently.

CoolLED Recruitment

CoolLED is Recruiting

CoolLED has a great opportunity for a Goods In/Out Operative to join our growing Manufacturing team.

Congratulations to the winner of the Nanolive/CoolLED Scientists of Tomorrow Competition.

Congratulations to the winner of the Nanolive/CoolLED Scientists of Tomorrow Competition.

CoolLED are very please to announce that Valentina Palacio-Castaneda is the winner of our undergraduate contest, ‘Scientists of Tomorrow’.

CoolLED Recruitment

CoolLED is Recruiting

Due to strong growth in its core market and opportunities to expand CoolLED is looking to strengthen its R&D department with a Product Development Manager

Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit

Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit

Obesity and its health effects is a major problem and that is becoming more prevalent. Researching the cells in the brain that are affected by food intake and satiety mechanisms is important and may lead to other forms of intervention beyond dietary control.

CoolLED are proud to announce 10 years collaboration with Medipan

CoolLED are proud to announce 10 years collaboration with Medipan

The CoolLED team had a great time visiting its partners Medipan recently. It was also a perfect opportunity to present them with an award in celebration of 10 years successful collaboration.

CoolLED Ambassadors for Teen Tech

CoolLED Ambassadors for Teen Tech

CoolLED had a remarkable time yesterday at the local Teen Tech event in Basingstoke.

LED Light Sources

Self-organized centripetal movement of corneal epithelium in the absence of external cues

This recent article in Nature Communications is an intriguing example of marrying a mathematical model of cell fate tracing with biology data

CoolLED Recruitment

CoolLED is Recruiting

CoolLED has an exciting opportunity for a Mechanical Design Engineer to join our growing R&D team

CoolLED welcomes Nick Sullivan

CoolLED welcomes Nick Sullivan

CoolLED is very pleased to welcome Nick Sullivan to the team as Production Engineer.

Welcome to the team – Alex Gramann

Welcome to the team – Alex Gramann

CoolLED is pleased to welcome Alex Gramann to the R&D Team. Alex joins us as Product Development Engineer.

Open Calcium Conference 12th July

Open Calcium Conference 12th July

CoolLED is excited to be sponsoring the Open Calcium Conference this year on 12th July. Our CoolLED team will be there to greet you and demonstrate our pE-340fura.

CoolLED welcomes Chris Deeks to the team

CoolLED welcomes Chris Deeks to the team

CoolLED is excited to welcome Chris Deeks to the team. Chris joins us as Field Sales Manager for UK and Ireland.

Welcome to the Team – Brad Reynolds

Welcome to the Team – Brad Reynolds

It is with great pleasure that CoolLED welcomes Brad Reynolds to the team. Brad will be responsible for field sales management across the US East Coast.

Welcome to the team Danielle Love

Welcome to the team Danielle Love

CoolLED is pleased to welcome Danielle Love to the team.. Danielle will be the Field Sales Manager for Southern & Central Europe

Undergraduate contest “Scientists of Tomorrow”

Undergraduate contest “Scientists of Tomorrow”

CoolLED & Nanolive invite you to participate in the undergraduate contest “Scientists of Tomorrow”

CoolLED welcomes Brynn Dachtler to the Team

CoolLED welcomes Brynn Dachtler to the Team

CoolLED are pleased to welcome Brynn Dachtler to the team. Brynn has joined the R&D Team as a Development Engineer.

Distributor+ Alan Tilley with Atlantic Imaging spreading the word on CoolLED

Distributor+ Alan Tilley with Atlantic Imaging spreading the word on CoolLED

European Placement Network brings Daniston Lenie-Franco to CoolLED

European Placement Network brings Daniston Lenie-Franco to CoolLED

We are proud to welcome Daniston LENIE-FRANCO, a French student studying a masters degree in Mechanical Engineering.

LED light for microscope

How our CoolLED pE-300 contributes to Marine Science Research

This paper interested me in two main ways. Firstly it is an area of research that I’m unfamiliar and secondly it was an unusual use of one of our LED light sources in fluorescence microscopy.

Applying microscopy to understand skin fragility disorders

Applying microscopy to understand skin fragility disorders

Epithelial cells and the sheets they produce, including our skin, are incredibly strong thanks
to their internal keratin filament cytoskeleton networks

CoolLED pE-4000 working with cultured hippocampal neurons.

CoolLED pE-4000 working with cultured hippocampal neurons.

At Eötvös Lóránd University we investigate activity-dependent forms of synaptic plasticity and homeostatic regulation of intrinsic excitability of mouse hippocampal neurons.

DAPI to Cy7 and Beyond – There is a Real Buzz to our Light this Year.

DAPI to Cy7 and Beyond – There is a Real Buzz to our Light this Year.

From April 2018 the pE-4000 will benefit from improved LED technology giving enhanced intensity and reduced power usage.

Would you like to be part of this?

Hearing how CoolLED LED Illumination Systems contribute to and improve the work of our customers fills us with a great deal of satisfaction and pride!

CoolLED welcomes Lynsey Burton to the team!

CoolLED welcomes Lynsey Burton to the team!

Lynsey offers a wide range of experience in microscopy and imaging techniques which will be valuable to CoolLED customers.

New Optogenetic Tools Tested with a CoolLED pE-4000

New Optogenetic Tools Tested with a CoolLED pE-4000

This is a superb paper on engineered optogenetic tools that shift wavelengths from the normal excitation wavelengths, which also have stability in vivo and have altered kinetics

Reduce the increasing burden of human fungal disease in the developed and developing world.

Reduce the increasing burden of human fungal disease in the developed and developing world.

The Manchester Fungal Infection Group (MFIG) was created in 2013 within the University of Manchester

Distributor+ Grant Hurley with Opto UK showing our CoolLED pE-300 Series

Distributor+ Grant Hurley with Opto UK showing our CoolLED pE-300 Series

It’s great to see one of our CoolLED Distributor+ companies Opto UK, spreading the word on the CoolLED pE-300 Series Illumination Systems

CoolLED Recruitment

CoolLED is recruiting

CoolLED is seeking to increase its sales resources in the US by recruiting a Field Sales Manager to continue development of its business on the East Coast.

LEDs v Mercury Bulbs – Case Study

LEDs v Mercury Bulbs – Case Study

Andy Evans of Green Light Laboratories has carried out independent testing of a CoolLED Illumination System compared with a traditional mercury bulb.

LEDs in Microscopy – Improved Imaging with Reduced Impact on the Environment

LEDs in Microscopy – Improved Imaging with Reduced Impact on the Environment

Case study written by Martin Farley, Research Efficiency Manager at Kings College London.

Guaranteed Delivery by Christmas…

Guaranteed Delivery by Christmas…

Last order dates for delivery before Christmas are…

CoolLED Recruitment

Career Opportunities at CoolLED

Due to continuing growth and expansion CoolLED have exciting career opportunities available

Choice of Illumination System & Fluorophore for Multiplex Immunofluorescence on FFPE Tissue Sections

Choice of Illumination System & Fluorophore for Multiplex Immunofluorescence on FFPE Tissue Sections

A review by Dr Robert Hartley, CoolLED

i2SL Go Beyond Award Winners!

i2SL Go Beyond Award Winners!

CoolLED is very proud to have received an award for its pE-300 Series LED Illumination Systems.

Epifluorescence Imaging and Optogenetic Stimulation for In-vitro Electrophysiology

Epifluorescence Imaging and Optogenetic Stimulation for In-vitro Electrophysiology

Alessandro Galloni of The Francis Crick Institute, discusses patch-clamp electrophysiology, a widespread method for analyzing the intrinsic properties of neurons and the local connections between them.

CoolLED is certified to ISO 9001:2015 Quality Management Standard

CoolLED is extremely proud to announce that we are now certified to ISO 9001:2015 Quality Management Standard.

Do LEDs really save you money over mercury or Metal Halide on your fluorescent microscope?

Do LEDs really save you money over mercury or Metal Halide on your fluorescent microscope?

CoolLED is proud to be taking LED efficiency to the next level.

A cycle-logically challenging Duathlon, but the team did wheelie well!

The CoolLED duathlon was back again last week, this year raising money for a great local charity – The Andover VIPs.

CoolLED win Test Valley Business Award for Innovation & Technology

CoolLED win Test Valley Business Award for Innovation & Technology

CoolLED is really proud to have been awarded the Test Valley Business Award for Innovation & Technology at a ceremony last night.

LED Illumination for Fura-2 Calcium Imaging – check out this paper published in Journal of Microscopy

LED Illumination for Fura-2 Calcium Imaging – check out this paper published in Journal of Microscopy

The pE-340fura will be launched this month!

CoolLED pE-340fura is on the way.

CoolLED pE-340fura is on the way.

Launching in September 2017, the pE-340fura will offer; Speed, Stability & Cell Viability

CoolLED pE-340fura

Fast and FURAous-2: The next instalment just gets faster and brighter.

CoolLED is excited to be launching the pE-340fura, a bespoke LED Illumination System for Fura-2 ratiometric calcium imaging, in September 2017

Fast, Controllable LED Illumination for Fura-2

Fast, Controllable LED Illumination for Fura-2

Achieved through partnership with The University of Strathclyde, CoolLED are excited to announce the latest leap forward in LED illumination for microscopy.

Bespoke 340/380nm LED Illumination for Fura-2 Calcium Imaging

Bespoke 340/380nm LED Illumination for Fura-2 Calcium Imaging

CoolLED will launch a fast controllable LED illumination system for ratiometric calcium imaging in September 2017 – the pE-340fura.

Best Poster Awarded to Peter Tinning at Photonex

Best Poster Awarded to Peter Tinning at Photonex

Huge congratulations to Peter Tinning who won the best poster award at the Photonex Conference last week.

Using Optogenetics to Analyse Neuronal Circuits

Using Optogenetics to Analyse Neuronal Circuits

Dr Max Anstotz of University Medical Center Hamburg-Eppendorf, discusses how analysing neuronal circuits is crucial for the understanding of basic and complex cortical functions.

Professor Gail McConnell presents “The Mesolens” in Venice

Professor Gail McConnell presents “The Mesolens” in Venice

Professor Gail McConnell’s recent presentation at the Nanoscale Optical Microscopy Meeting in Venice, was very well received. Read the abstract and download the the presentation slides here…

CoolLED Recruitment

Production Engineer Opportunity at CoolLED

Due to continuing growth and expansion CoolLED have an exciting opportunity for an electro-mechanically minded Production Engineer

It’s getting intense at CoolLED!

It’s getting intense at CoolLED!

Double the GREEN intensity – view and image your samples easier than ever…

What we Owe to the Invention of the Microscope

What we Owe to the Invention of the Microscope

Cutting-edge advancements like the Mesolens from Brad Amos and Gail McConnell trace back to the very first microscopes built in the 16th and 17th centuries was the subject of a great article in the Smithsonian in March 2017…

Great to see Izasa Scientific

Great to see Izasa Scientific

Great to have our friends Izasa Scientific over to visit our UK site last week

CoolLED Recruitment

Dynamic, enthusiastic individual required for Field Sales Manager role at CoolLED

CoolLED is seeking to increase its sales resources by recruiting an additional Field Sales Manager to continue development of its business.

CoolLED hosts local high-tech symposium

CoolLED hosts local high-tech symposium

CoolLED was pleased to host the first symposium of leading Andover-based companies to discuss their requirements for high technology staff, infrastructure and training.

Extended Software Integration – Latest News 7

Extended Software Integration – Latest News 7

CoolLED is extending its integration into major software platforms. This month’s focus is μManager

CoolLED – the company you can trust with on time despatch

CoolLED – the company you can trust with on time despatch

Customers want suppliers they can depend upon, who can despatch when they say they will. Our goal at CoolLED is customer satisfaction…

CoolLED welcomes Ian Patterson to the team

CoolLED welcomes Ian Patterson to the team

CoolLED is extremely pleased to welcome Ian Patterson as the new Sales & Marketing Director.

Wide Area Illumination from CoolLED for Curing Applications

Wide Area Illumination for Curing Applications

CoolLED, a leader in high end microscopy illumination has recently taken its technological know-how into wide area illumination for UV curing applications.

CoolLED Recruitment

Sales Support opportunity at CoolLED

CoolLED have an exciting opportunity within Sales Support

pE-4000 lights the way for the Mesolens – New Publication in eLife

pE-4000 lights the way for the Mesolens – New Publication in eLife

New Mesolens publication has now been accepted and published by eLife

Nick Edwards Gold Award – and the winner is…

Nick Edwards Gold Award – and the winner is…

In memory of an inspirational man, the team at CoolLED wanted something which embodied Nick Edwards’ way of working. We therefore created the Nick Edwards Gold Award which was presented for the first time this year.

Precisely controlled illumination for high speed fluorescence microscopy

Precisely controlled illumination for high speed fluorescence microscopy

CoolLED’s Fast Controllable Illumination System launching at Neuroscience 2016

CoolLED Duathlon Success!

CoolLED Duathlon Success!

Great effort, enthusiasm and team spirit was shown on Friday 14th October, as the CoolLED team took part in their very own Duathlon event.

CoolLED on a Mission

CoolLED on a Mission

The CoolLED team had a fantastic day celebrating their 10th anniversary recently.

pE-300ultra LED illumination designed for optogenetics on the microscope

pE-300ultra LED illumination designed for optogenetics on the microscope

Utilising the technology from CoolLED’s massively successful pE-300 Series the pE-300ultra includes the same broad spectrum coverage and highly usable LED’s as other members of the pE-300 Series.

Reseller spreading the word…

Reseller spreading the word…

It’s great to see one of our resellers, Microscopes South West, spreading the word on the CoolLED pE-Series Illumination Systems.

Illumination for fluorescence microscopy can be simple with the NEW pE-300lite

Illumination for fluorescence microscopy can be simple with the NEW pE-300lite

With 10 years’ experience, CoolLED wanted to make an illumination product which is accessible to all. The NEW pE-300lite from CoolLED is all about simplicity.

pE-4000

Are you still using mercury and halide bulbs?

Are you hanging onto mercury or metal halide because you worry that whilst LED systems give you great stability & control with low running costs, you will lose the flexibility of a traditional light source?

10th Anniversary and CoolLED’s on the move

10th Anniversary and CoolLED’s on the move

CoolLED Ltd. is preparing to celebrate its 10th anniversary as the company which introduced the first LED illumination system to the microscopy world.

New Management Team for CoolLED Ltd.

New Management Team for CoolLED Ltd.

Not only is CoolLED preparing to celebrate 10 years of leading the way in fluorescence illumination for microscopy, but the new management team at CoolLED Ltd. is excited by the acquisition by Judges Scientific.

Switch to LED Illumination for your Fluorescence Microscopy

Switch to LED Illumination for your Fluorescence Microscopy

When it comes to fluorescence microscopy, the new pE-300lite from CoolLED is all about simplicity.

Looking to Get Rid of Mercury – Now’s the Time to Switch to LEDs

Looking to Get Rid of Mercury – Now’s the Time to Switch to LEDs

There are serious environmental and health-hazards to consider if you’re still using Mercury – read more…

Not sure if LEDs are right for your application?

Not sure if LEDs are right for your application?

Over 100 searchable abstracts/papers to look at…

Extended Software Integration – Latest News 6

Extended Software Integration – Latest News 6

CoolLED is extending its integration into major software platforms. This month’s focus is Andor’s – Andor iQ

New Managing Director for CoolLED Ltd

New Managing Director for CoolLED Ltd

CoolLED Ltd, the first company to introduce LED illumination to microscopy, has a new Managing Director.

CoolLED Recruitment

Fantastic opportunity at CoolLED for a Sales & Marketing Director

CoolLED is seeking a Sales & Marketing Director to drive the next chapter in an impressive growth story.

Chroma filter sets optimised for CoolLED Illumination Systems

Chroma filter sets optimised for CoolLED Illumination Systems

Filter manufacturers are developing filter sets optimised for LEDs…

Optogenetics technique benefits from the pE-4000 Illumination System

Optogenetics technique benefits from the pE-4000 Illumination System

Fast Gamma Oscillations Are Generated Intrinsically in CA1 without the Involvement of Fast-Spiking Basket Cells

Webinar training – a shift in paradigm

Webinar training – a shift in paradigm

Webinar training sessions are leading the way…

Extended Software Integration – Latest News 5

Extended Software Integration – Latest News 5

CoolLED is extending its integration into major software platforms. This month’s focus is Hamamatsu – HCImage

Dr Brad Amos FRS presents Student Poster Prize

Dr Brad Amos FRS presents Student Poster Prize

Best Student Poster Prize at the EMBO Practical Course in Advanced Optical Microscopy goes to…

The pE-4000 lights the way for the University of Strathclyde’s Mesoscope

The pE-4000 lights the way for the University of Strathclyde’s Mesoscope

Prof Gail McConnell and Dr Brad Amos FRS describe the new Mesolens set up at the University of Strathclyde

Extended Software Integration – Latest News 4

Extended Software Integration – Latest News 4

CoolLED is extending its integration into major software platforms. This month’s focus is Olympus – cellSens…

Sad News from CoolLED

Sad News from CoolLED

It is with great sadness that we announce the untimely loss of our founder and chairman, Nick Edwards…

CoolLED Ltd. has been purchased by Judges Scientific plc

CoolLED Ltd. has been purchased by Judges Scientific plc, an AIM-listed company, to become the eleventh company to join the group which specialises in the design and production of scientific instruments.

Welcome to OEMIllumination

Welcome to OEMIllumination

With our focussed team of engineers in place and ready to start new collaborations, we have chosen Photonics West to launch our specialist OEMillumination.com website.

CoolLED’s NEW Applications Resource

CoolLED’s NEW Applications Resource

See how CoolLED’s LED solutions have been successfully used in an extensive range of applications…

Proud to Introduce the CoolLED Team!

Proud to Introduce the CoolLED Team!

CoolLED is growing fast so we thought it would be nice for you to see the faces behind the names of the people you speak to frequently…

Lisa Stevens joins the CoolLED team

Lisa Stevens joins the CoolLED team

We are pleased to welcome Lisa Stevens to CoolLED as Quality & Compliance Manager.

Extended Software Integration – Latest News 3

Extended Software Integration – Latest News 3

CoolLED is extending its integration into major software platforms. This month’s focus is Molecular Device’s – MetaMorph series…

LEDs in Biology Research: From Microscopy to Optogenetics

LEDs in Biology Research: From Microscopy to Optogenetics

Published article by our very own Dr Robert Hartley…

Extended Software Integration – Latest News 2

Extended Software Integration – Latest News 2

CoolLED is extending its integration into major software platforms. This month’s focus is Nikon’s NIS Elements…

CoolLED Recruitment

Production Engineer Opportunity at CoolLED

Due to continuing growth and expansion CoolLED have an exciting opportunity for an electro-mechanically minded Production Engineer

CoolLED Recruitment

Are you an Experienced Product Development Engineer looking for a new challenge?

Due to continuing growth and expansion, CoolLED have an exciting opportunity for a Product Development Engineer to join the team and support with R&D development.

Extended Software Integration – Latest News

Extended Software Integration – Latest News

CoolLED is extending it’s integration into major software platforms. This month’s focus is Leica’s LASX…

CoolLED pushes the limits of Fluorescence Illumination with the University of Strathclyde

CoolLED pushes the limits of Fluorescence Illumination with the University of Strathclyde

We’re delighted to announce a new collaboration with the University of Strathclyde.

Dr Robert Hartley joins the CoolLED team

Dr Robert Hartley joins the CoolLED team

We are very pleased to welcome Dr Robert Hartley to CoolLED as Field Sales Manager.

CoolLED Recruitment

Experienced Mechanical Design Engineer required

CoolLED has an exciting opportunity for a Mechanical Design Engineer to join our growing R&D team.

Semrock filter sets optimised for CoolLED pE-4000

Semrock filter sets optimised for CoolLED pE-4000

Semrock’s LED illumination system filter sets optimised for the pE-4000

CoolLED support Cold Spring Harbor Courses

Through our partnership with Scientifica, we have been able to provide CoolLED fluorescence illumination systems to the electrophysiology and optogenetics scientist.

CoolLED are proud supporters of the MBL Summer Educational Program

The Marine Biological Laboratory’s (MBL) 2015 Summer Educational Program is imminent and loan equipment is crucial to it’s success…

See the CoolLED pE-300white at ELMI

See the CoolLED pE-300white at ELMI

See the pE-300white at ELMI 2015 on Andor Technology booth~GM15

CoolLED product at ELMI 2015

CoolLED product at ELMI 2015

See CoolLED product at ELMI 2015 on our OEM customer booths

CoolLED Recruitment

Dynamic, enthusiastic individual required for Field Sales Manager role

CoolLED is seeking to increase its sales resources by recruiting an additional Field Sales Manager to continue development of its business.

Congratulations to Kirti Prakesh – Poster Prize winner from Mainz Institute of Molecular Biology

Congratulations to Kirti Prakesh – Poster Prize winner from Mainz Institute of Molecular Biology

Dr Brad Amos FRS awards Kirti Prakesh with his prize at the recent EMBO Practical Course in Advance Optical Microscopy.

Kit Malthouse visits CoolLED

Kit Malthouse visits CoolLED

Kit Malthouse, Conservative Parliamentary Candidate for North West Hampshire, recently visited CoolLED’s offices at Westmarch Business Centre in Andover

CoolLED Recruitment

CoolLED is recruiting

Due to continuing growth and expansion, CoolLED have an exciting opportunity for a Software Engineer to join the team

CoolLED Recruitment

CoolLED is recruiting

Due to continued growth we have a vacancy in our technical department for a full time Development Engineer.

CoolLED product at Biophysical Society 59th Annual Meeting

See CoolLED product at the Biophysical Society’s 59th Annual meeting at Baltimore Convention Center, on February 7-11, 2015.

CoolLED Recruitment

CoolLED is recruiting

Due to continued growth we have a vacancy in our production department for a full time Production Operative.

Better Control of Light with the pE-300white

Better Control of Light with the pE-300white

CoolLED is pleased to announce that additional functionality on the pE-300white is now available on all these systems. Software control via a USB interface is now included.

We will support you…

CoolLED pE-Series LED Illumination systems have a full 12-month return-to-base warranty. LAMs (LED Array modules) enjoy a 36-month warranty. If you are experiencing any problems, firstly refer to the User Manual. Thereafter, you can access support from CoolLED either by phone or email.

New Industry Collaboration

CoolLED Limited, a UK-based manufacturer of LED fluorescence illumination products is delighted to announce that Prior Scientific, has chosen CoolLED as their OEM partner in a collaborative enterprise to satisfy Prior’s customers’ requirements for LED illumination. Response to this collaboration has been exceptional and continues to grow.

CoolLED Recruitment

CoolLED is recruiting

Due to continued growth and success, CoolLED have an exciting opportunity for a Junior Administrator to join the team and support our Administration department.

Neuroscience 2014

Neuroscience 2014

CoolLED exhibited its successful new generation pE-4000 universal illumination system at the meeting in Washington this month.

pE-4000

NEW Generation pE-4000 LED illumination systems from CoolLED

The pE-4000 represents the ultimate in capability and functionality of any fluorescence illumination system

See CoolLED at Neuroscience 2014

See CoolLED at Neuroscience 2014

Are you attending Neuro this year? If so, we would like to invite you to come and see CoolLED’s NEW GENERATION LED Illumination Systems and meet the team, on Booth # 2634.
Due to the busy nature of the show, if you would like to book a specific appointment, please click here

LED Microscope Illuminator

NEW Generation LED illumination systems from CoolLED

Recent developments in the application of LED technology have resulted in illumination systems offering increased brightness for fluorescence microscopy.

Exciting changes at CoolLED USA

Exciting changes at CoolLED USA

Following the response to CoolLED’s NEW generation illumination systems from our US users, the company is making further investment in developing its support network and relationships with key suppliers to the microscopy world.

Luther Hindley joins the CoolLED team

Luther Hindley joins the CoolLED team

We are very pleased to welcome Luther Hindley to the CoolLED team as NPI Engineer. He will have particular responsibility for supporting the transition of new products from R&D to Manufacturing, as CoolLED continues to grow its product range.

CoolLED success at NIH Research Festival Exhibit

CoolLED success at NIH Research Festival Exhibit

Industry interest in CoolLED’s capabilities was exceptionally high at NIH Research Festival Exhibit last week.

Visualizing Cancer: Microscopy and Beyond – Poster winner

Visualizing Cancer: Microscopy and Beyond – Poster winner

A specialised symposium on the application of advanced imaging in the field of cancer biology was held earlier this month, at the Beatson Institute For Cancer Research in Glasgow.

CoolLED were very happy to support the meeting and would like to congratulate Georgios Kanellos on winning 1st prize for best poster.

CoolLED’s customer wins award for innovation

CoolLED’s customer wins award for innovation

One of CoolLED’s key distributors, Abberior Instruments GmbH, has also been successful in winning a Microscopy Today Innovation Award in conjunction with the Max Planck Institute for Ultraparallel RESOLFT Super resolution Microscopy.

The hazards of a blown mercury bulb…

The hazards of a blown mercury bulb…

Al Shipman of the Royal Liverpool NHS Hospital in the UK commented that he fitted a CoolLED pE-300white solid state LED illumination system after an incident in his lab with a blown mercury bulb.

CoolLED Recruitment

CoolLED is recruiting

CoolLED wins Microscopy Today Innovation Award 2014 for the pE-4000

CoolLED wins Microscopy Today Innovation Award 2014 for the pE-4000

CoolLED’s pE-4000 Universal LED Fluorescence Illumination System wins the prestigous Microscopy Today Innovation Award 2014.

Did you see CoolLED at MMC 2014?

Did you see CoolLED at MMC 2014?

CoolLED’s range of products were on show at MMC 2014, not only on the CoolLED booth, but also all around the exhibition hall, including the Learning Zone.

CoolLED’s New Website!!

CoolLED’s New Website!!

CoolLED is pleased to launch its new website. With an exciting new range of LED illumination systems, the website is presented to make learning about these products simpler and easier.

CoolLED - ELMI 2014

CoolLED will be at ELMI 2014

CoolLED will participate again at the European Light Microcopy Initiative meeting to be held at Holmenkollen Park Hotel Rica in Oslo, Norway

CoolLED Recruitment

CoolLED is recruiting

CoolLED Ltd designs, develops and manufactures LED illumination products, principally for use in microscopy..

CoolLED Recruitment

CoolLED is recruiting

CoolLED is seeking to increase its sales resources by recruiting an additional Field Sales Manager to continue development of its..

CoolLED - LEDs save energy & money

CoolLED LEDs save energy & money!

Conventional mercury-based light sources such as arc lamps and metal-halide lamps require a warm-up period before use and a cool-down..

CoolLED LED illumination systems as seen on TV!

CoolLED LED illumination systems – As seen on TV!

The Royal Institutions annual Christmas Lectures have been running since 1825 – this year’s topic was “Life Fantastic”..

Better Control of Light with the pE-300white

Better Control of Light with the pE-300white

CoolLED is pleased to announce that additional functionality on the pE-300white is now available on all these systems. Software control via a USB interface is now included.

CoolLED Recruitment

CoolLED is recruiting

CoolLED Ltd designs, develops and manufactures LED illumination products, principally for use in microscopy..

CoolLED Recruitment

CoolLED is recruiting

CoolLED is seeking a Field Sales Manager to develop its business in North America. The opportunity is for a dynamic..

CoolLED’s pE-4000 selected as finalist

CoolLED’s pE-4000 selected as finalist

We are pleased to announce that CoolLED’s new pE-4000 has been selected as a finalist entry for the 2014 Photonics PRISM Awards

The Universal LED Light Source from CoolLED

The Universal LED Light Source from CoolLED

CoolLED Ltd.announces the launch of its new pE-4000 LED source. This new product sets the standard as the universal light source..

LED Microscope Illuminator

The CoolLED pE-300-White has arrived

From the company that brought LEDs to fluorescence microscopy, CoolLED’s latest product, the new pE-300-White, brings..

Environment & Safety

Did you know that LED illumination systems help laboratories reduce their carbon footprint, protecting laboratory staff along the way?

Toxic mercury-based microscope illuminators are bad news for the environment, draw a lot of power and have a short lifetime.

LED illumination systems are cleaner, have a long lifetime and use less power. Our pE-300 Series is also ACT label certified and is a natural choice for labs who want to play their part in helping the environment.

Help & Advice

At CoolLED we are committed to giving our customers outstanding service right from the start and throughout the lifetime of the product. Please get in touch if you have any questions or would like a quote. You can also browse our site for technical resources and general support.

UK +44 (0)1264 323040
USA 1.800.877.0128