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  • About
    • CoolLED Mission
    • Meet The Team
    • Compliance
  • Products
    • Product Comparison
    • pE-100
    • pT-100
    • pE-300 Series
      • pE-300lite
      • pE-300white
      • pE-300ultra
      • pE-300opto
    • pE-340fura
    • pE-400 Series
      • pE-400
      • pE-400max
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      • pE-800
      • pE-800fura
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  • OEM Multiplexing
    • pE-10
  • Support
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  • Resources
    • Resource Library
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    • No More Mercury – The Phase Out of Mercury & Metal Halide Bulbs
    • Climate Action
    • Gender Equality / Reduce Inequalities
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Category Archives: Blog

Multiplexing: Because One Fluorophore Was Too Easy

Multiplexing: Because One Fluorophore Was Too Easy

April 24, 2026

‘Multiplexing’ might sound like the sort of word that should belong in a cinema, or a very complicated tax return, but let’s take a closer look…

Still Using Mercury or Metal Halide? Let’s Make a Plan

Still Using Mercury or Metal Halide? Let’s Make a Plan

April 17, 2026

Before your last spare bulb starts being treated like a sacred relic, take a look at what you have, how quickly you use it, and how long it’s realistically likely to last…

From Concept to Commerce – Insights from my time at CoolLED

From Concept to Commerce – Insights from my time at CoolLED

April 10, 2026

Good imaging starts with good light. A neuroscience student reflects on phototoxicity, data quality, and her time at CoolLED…

Mercury Phase-Out Panic? Take the Readiness Quiz

Mercury Phase-Out Panic? Take the Readiness Quiz

April 3, 2026

The move from mercury and metal halide to LED illumination doesn’t need to be rushed, stressful or wildly expensive all at once… But it does need to start somewhere

Is Your Light Source the Problem? 5 Common Fluorescence Imaging Frustrations Explained

Is Your Light Source the Problem? 5 Common Fluorescence Imaging Frustrations Explained

March 27, 2026

Get your illumination right and a lot of things get easier. Results feel more consistent. Switching gets quicker. Imaging becomes less of a battle. Which is really the whole point…You’ve got enough going on already.

Spring Clean Your Fluorescence Microscopy Setup

Spring Clean Your Fluorescence Microscopy Setup

March 20, 2026

Spring is a good time to refresh your fluorescence microscopy setup and rethink whether outdated illumination is holding your lab back.

Mercury Lamp Phase-Out in Fluorescence Microscopy: Your Questions Answered

Mercury Lamp Phase-Out in Fluorescence Microscopy: Your Questions Answered

March 13, 2026

The mercury lamp phase-out is approaching in 2027. If you’re wondering what it means for your microscope setup, our No More Mercury FAQs are a good place to start.

The Mercury Bulb Phase-Out: Wherever You Are in the Conversation, We’re Here to Help

The Mercury Bulb Phase-Out: Wherever You Are in the Conversation, We’re Here to Help

March 6, 2026

Starting the conversation early makes things easier. One of the advantages of knowing about the phase-out ahead of time is that it gives labs space to think about their options calmly.

How Long Will Your Mercury Bulb Stock Actually Last?

How Long Will Your Mercury Bulb Stock Actually Last?

February 27, 2026

Very few facilities actively and accurately track their mercury or metal halide bulb usage over time. They get ordered, installed, replaced, and eventually forgotten about.  But this creates a blind spot…

Introducing the pE-300opto: A Simple, Precise Light Source for Optogenetics

Introducing the pE-300opto: A Simple, Precise Light Source for Optogenetics

February 20, 2026

Optogenetics is all about precise control: the right wavelength, the right intensity, the right timing.  The pE-300opto is built to deliver exactly that, offering just the wavelengths and control that matter, in a compact, affordable package.

CoolLED supports EBP South “Get Inspired”

CoolLED supports EBP South “Get Inspired”

February 13, 2026

We recently attended EBP South’s ‘Get Inspired’ event, where Marina, Alex and Andrew spent a busy day speaking with young people about careers in STEM

Top 5 Signs Your Microscope Setup Is Working Against You

Top 5 Signs Your Microscope Setup Is Working Against You

February 6, 2026

Have you ever felt like your microscope has a slight vendetta against you?  It seems to works okay for everyone else, but for you it’s like trying to convince a really tired toddler to put their shoes on?  Chances are, it might not be your fault…

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Custom Microscopy Illumination

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For manufacturers who wish to gain a competitive advantage through bright, stable and controllable illumination, CoolLED’s world-renowned LED technology is available in customised configurations.

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OEM Family Range

Sustainability

Did you know that LED illumination systems help laboratories reduce their carbon footprint, protecting laboratory staff along the way?

Toxic mercury-based microscope illuminators are bad news for the environment, draw a lot of power and have a short lifetime.

LED illumination systems are cleaner, have a long lifetime and use less power. Our pE-300 Series is also ACT label certified and is a natural choice for labs who want to play their part in helping the environment.

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Help & Advice

At CoolLED we are committed to giving our customers outstanding service right from the start and throughout the lifetime of the product. Please get in touch if you have any questions or would like a quote. You can also browse our site for technical resources and general support.

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