The Power of Imaging Software in Fluorescence Microscopy
In the world of fluorescence microscopy, precise control of LED illumination is crucial for obtaining high-quality images and reliable data.
One of the key strengths of our Illumination Systems is their compatibility with a wide range of third-party imaging software.
By integrating our light sources with external software, researchers can streamline their workflows and take full control of their microscopy setups, unlocking greater flexibility and precision.
Advantages of Controlling LED Illumination with Imaging Software
Using imaging software to control your CoolLED light source offers several key benefits:
- Seamless Integration: Many of our LED illumination systems are compatible with popular third-party imaging software, allowing researchers to manage both their light source and imaging acquisition from a single platform.
- Automation and Efficiency: Software control simplifies routine processes by automating the switching of wavelengths, intensity adjustments, and timing sequences. This is particularly useful for experiments that require rapid, repeatable actions, such as time-lapse imaging or live-cell imaging.
- Precision Control: Adjusting LED light sources via software provides more granular control over illumination settings, which is essential for achieving consistent, high-quality images.
- Flexibility Across Applications: Whether you are working in a university lab or a research institute, software-controlled LED illumination can be easily adapted to suit the specific needs of your experiment, reducing manual intervention and enhancing productivity.

Lightning-Fast TTL Switching for Greater Efficiency
In addition to software compatibility, most CoolLED fluorescence microscope illumination systems can also be operated remotely using TTL (Transistor-Transistor Logic) signals for simple, efficient channel on/off control. This feature is particularly valuable for high-speed applications, where fast switching of light sources is essential.
- Less than 7 Microseconds Switching (pE-800): The pE-800 Series LED light source can achieve lightning-fast switching speeds of less than 7 microseconds via TTL control. This near-instantaneous response time ensures that you capture exactly the data you need, without any delay in switching between channels.
- Applications of Fast TTL Switching: Fast switching is especially beneficial for applications such as optogenetics, high-speed calcium imaging, and fast live-cell imaging, where precise timing and rapid transitions between light channels are critical for successful experimentation.
By using TTL signals, researchers gain an extra layer of control over their light sources, improving the accuracy and timing of their imaging processes.
VisiView Software Now Supports pE-400 Series
We’re excited to announce that VisiView software, developed by Visitron, has now been updated to include our industry-leading pE-400 Series. This update adds yet another powerful tool to the pE-400 Series’ already impressive arsenal.
- Improved User Experience: VisiView’s integration with the pE-400 Series simplifies illumination control and enhances usability. Whether you’re switching channels or adjusting intensity, the seamless connection between the software and the LED system offers a smooth, intuitive user experience.
- Streamlined Workflows: With VisiView on board, researchers using the pE-400 Series can enjoy even greater control over their illumination settings, simplifying the process of capturing high-quality fluorescence images.
This collaboration between CoolLED and Visitron is another example of how we continue to provide our customers with cutting-edge solutions that enhance their research and imaging capabilities.
The combination of our LED light sources with third party imaging software, offers significant advantages for researchers – from improved control and automation to greater flexibility and precision. Whether you choose to operate your light source via software or through lightning-fast TTL signals, our solutions are designed to optimise your microscopy workflow.
With the addition of VisiView support for the pE-400 Series, wecontinues to deliver tools that make fluorescence microscopy more accessible and efficient.
In short, our LED Illumination Systems, paired with the right software, provide a powerful and flexible foundation for cutting-edge research.








