Control Your CoolLED Microscope Illuminator in Leica LAS X
Configuring complex imaging experiments is faster and more efficient when the microscope light source is directly integrated into imaging software.
We are now pleased to share that the CoolLED pE-300 Series, pE-400max and pE-800 Series Illumination Systems are fully supported in Leica LAS X imaging software.
What’s New?
This integration allows users to control illumination settings directly from the LAS X environment, streamlining workflows and improving experimental consistency.
For help with updating to compatible versions and setting up your system, follow our new Quick Start Guide or watch our tutorial video. In addition, Leica offers comprehensive tutorial content via the LAS X help menu.
About the pE-800 Series
The advanced pE-800 Series offers eight individually controllable LEDs, providing unparalleled flexibility for multi-channel fluorescence imaging.
About the pE-400max
The pE-400max provides up to four powerful LEDs with broad spectral coverage for a wide range of fluorophores, making it ideal for everyday fluorescence microscopy.
About the pE-300 Series
The compact and versatile pE-300 Series is designed for routine imaging applications, with broad compatibility across many microscopes and fluorophores.

Which Imaging Software programs can the CoolLED Illumination Systems be controlled in?
The CoolLED pE-300, pE-400 and pE-800 Series Illumination Systems are integrated into several imaging software platforms, including Leica LAS X, Nikon NIS-Elements and µManager. Integration allows seamless control of illumination settings directly from within the software environment, enhancing workflow efficiency and data reproducibility.
For a comprehensive overview of compatible platforms, consult our Imaging Software Table, where you’ll also find summary sheets, quick start guides, and, where available, video tutorials to help you get started.
In addition to software integration, the CoolLED product range offers many different control options, depending on the model you can compare product features here.




