Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition

Authors

Mie K Jakobsen, Sofie Traynor, Aaraby Y Nielsen, Christina Dahl, Mette Staehr, Simon T Jakobsen, Maria S Madsen, Rasmus Siersbaek, Mikkel G Terp, Josefine B Jensen, Christina B Pedersen, Anup Shrestha, Jonathan R Brewer, Pascal H G Duijf, Odd L Gammelgaard, Henrik J Ditzel, Alexei F Kirkin, Per Guldberg, Morten F Gjerstorff

Topic

Molecular Biology

Extract

"The images of stained MDA-MB-231 and MCF-cells were acquired with the Nikon Ti2 widefield microscope, equipped with CoolLED pE-300 white light source and Andor Zyla sCMOS camera."

Product Type

pE-300^white

Journal

Journal of Experimental and Clinical Cancer Research

Year of Publication

2025

Read the full research paper here

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