Lubiprostone Improves Distal Segment-Specific Colonic Contractions through TRPC4 Activation Stimulated by EP3 Prostanoid Receptor

Authors

Jeong B, Lee JH, Lee JA, Kim SJ, Lee J, So I, Jun JY, Hong C.

Topic

Calcium Imaging, Medical Research

Extract

"Ratiometric measurements of [Ca2+]i were performed using Fura-2-AM (Molecular Probes, Eugene, OR, USA). The cells were suspended and loaded with 2 μM of Fura-2-AM for 30 min at 37 °C. Fura-2 fluorescence was measured at 510 nm emission with 340/380 nm dual excitation using a pE-340 Fura illuminator (CoolLED, Andover, UK)."

Product Type

pE-340^fura

Journal

Pharmaceuticals (Basel)

Year of Publication

2024

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