In vivo spatiotemporal control of voltage-gated ion channels by using photoactivatable peptidic toxins

Authors

Jérôme Montnach,1,2 Laila Ananda Blömer,2,3 Ludivine Lopez,1,2,4 Luiza Filipis,2,3 Hervé Meudal,5 Aude Lafoux,6 Sébastien Nicolas,1,2 Duong Chu,7 Cécile Caumes,4 Rémy Béroud,4 Chris Jopling,8 Frank Bosmans,9 Corinne Huchet,6 Céline Landon,5 Marco Canepari,2,3 and Michel De Waardcorresponding author1,2,4

Topic

Biophotonics, Molecular Biology

Extract

"Illumination of samples was performed at 365 nm for different times (between 1 sec and 30 min illumination time) at 41.8 mW/cm2 or less (as specified in the Result section) for 10 min using a CoolLED pE4000 light source (CoolLED, UK)."

Product Type

pE-4000

Journal

Nature Communications

Year of Publication

2022

Custom Microscopy Illumination

Need something a little different?

For manufacturers who wish to gain a competitive advantage through bright, stable and controllable illumination, CoolLED’s world-renowned LED technology is available in customised configurations.

Streamlined development using proven off-the-shelf technology
Professional support
Market-leading warranty
‘Try before you buy’ option
Trusted experts in LED illumination technology since 2006

LEARN MORE

Environment & Safety

Did you know that LED illumination systems help laboratories reduce their carbon footprint, protecting laboratory staff along the way?

Toxic mercury-based microscope illuminators are bad news for the environment, draw a lot of power and have a short lifetime.

LED illumination systems are cleaner, have a long lifetime and use less power. Our pE-300 Series is also ACT label certified and is a natural choice for labs who want to play their part in helping the environment.