Closed-loop optogenetic control of cell biology enables outcome-driven microscopy

Authors

Josiah B Passmore, Alfredo Rates, Jakob Schröder, Menno T P van Laarhoven, Vincent J W Hellebrekers, Henrik G van Hoef, Antonius J M Geurts, Wendy van Straaten, Wilco Nijenhuis, Florian Berger, Carlas S Smith, Ihor Smal, Lukas C Kapitein

Topic

Biophotonics

Extract

"For epifluorescence illumination, a pE-4000 LED illumination system (CoolLED) was used as a light source, and ET 514 nm Laser Bandpass (Chroma, 49905) and ET mCherry (Chroma, 49008) filter cubes were placed in the lower filter turret.
For optogenetic illumination, a pE-800 LED illumination system (CoolLED) was used with a Mosaic 3 digital mirror device (Andor). "

Product Type

pE-4000, pE-800

Journal

Nature

Year of Publication

2025

Read the full research paper here

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