Capillary constrictions prime cancer cell tumorigenicity through PIEZO1

Authors

Giulia Silvani, Chantal Kopecky, Sara Romanazzo, Vanina Rodríguez, Ayan Das, Elvis Pandzic, John G Lock, Christine L Chaffer, Kate Poole, Kristopher A Kilian

Topic

Biophotonics, Calcium Imaging, Cell Biology, Time-Lapse Microscopy

Extract

"Using the same protocol of microcapillary-like constriction experiment, cells were injected into the microfluidic chip and were imaged using a CoolLED pE-4000 to illuminate the sample (488 nm illumination) on an Olympus IX70 inverted light microscope fitted with an Andor iXon EM-CCD camera and a 4X objective. "

Product Type

pE-4000

Journal

Nature Communications

Year of Publication

2025

Read the full research paper here

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