Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy

Authors

Célia Lentini,1 Marie d’Orange,1,8 Nicolás Marichal,2,3,8 Marie-Madeleine Trottmann,1 Rory Vignoles,1 Louis Foucault,1 Charlotte Verrier,1 Céline Massera,4 Olivier Raineteau,1 Karl-Klaus Conzelmann,5 Sylvie Rival-Gervier,6 Antoine Depaulis,4 Benedikt Berninger,2,3,7 and Christophe Heinrich1,9,∗

Topic

Neuroscience, Optogenetics

Extract

"iNs were visually identified on the basis of their fluorescence emission: DSRED+ (Ascl1/Dlx2) and GFP+ (ChR2, see below) using appropriate LED excitation (CoolLED pE-100) and emission filters, and were selected according to their neuronal morphology.
"

Product Type

pE-100

Journal

Cell stem cell

Year of Publication

2021

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