Conformational surveillance of Orai1 by a rhomboid intramembrane protease prevents inappropriate CRAC channel activation

Authors

Adam G. Grieve,1,∗ Yi-Chun Yeh,2,5 Yu-Fen Chang,3 Hsin-Yi Huang,3 Lucrezia Zarcone,1 Johannes Breuning,1,6 Nicholas Johnson,4,7 Kvido Stříšovský,4 Marion H. Brown,1 Anant B. Parekh,2 and Matthew Freeman1,8,∗∗

Topic

Calcium Imaging, Molecular Biology

Extract

"subsequently imaged on an inverted microscope (DMi8, Leica) equipped with a 63x objective lens (N.A. 1.4) and a multiwavelength LED light source (pE-4000, CoolLED) in regular Ca2+ containing solution.
"

Product Type

pE-4000

Journal

Molecular cell

Year of Publication

2021

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