{"id":10932,"date":"2021-07-23T10:38:22","date_gmt":"2021-07-23T10:38:22","guid":{"rendered":"https:\/\/www.coolled.com\/?post_type=app_notes&#038;p=10932"},"modified":"2021-07-27T10:46:15","modified_gmt":"2021-07-27T10:46:15","slug":"8-channel-microscopy-illumination-for-developing-novel-gene-therapeutics","status":"publish","type":"app_notes","link":"https:\/\/www.coolled.com\/technical-resources\/app-notes\/8-channel-microscopy-illumination-for-developing-novel-gene-therapeutics\/","title":{"rendered":"8-Channel Microscopy Illumination for Developing Novel Gene Therapeutics"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<img loading=\"lazy\" decoding=\"async\" title=\"Logo\" src=\"https:\/\/www.coolled.com\/wp-content\/uploads\/2021\/07\/Logo.png\" alt=\"Huida Gene logo\" width=\"200\" height=\"200\" class=\"size-full wp-image-10934 aligncenter\" srcset=\"https:\/\/www.coolled.com\/wp-content\/uploads\/2021\/07\/Logo.png 200w, https:\/\/www.coolled.com\/wp-content\/uploads\/2021\/07\/Logo-150x150.png 150w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/><\/p>\n<p>Based in Shanghai, Huida Gene is a biopharmaceutical organisation that develops and produces therapeutics such as gene replacement and gene editing for rare single-gene disorders and chronic diseases.<\/p>\n<p>In this application example, scientists used the <a href=\"https:\/\/www.coolled.com\/products\/pe-800\/\">CoolLED pE-800<\/a> on a Nikon ECLIPSE Ni-E microscope to scan tissue sections in order to determine the location of lesions. Cell climbing sheets were also imaged to count the cells and check their status. Multi-channel imaging was performed to visualise the nucleus with DAPI, the cytoskeleton with Alexa Fluor 488 and the mitochondria with Mitotrack Red.[\/vc_column_text][vc_single_image image=&#8221;10933&#8243; img_size=&#8221;large&#8221; add_caption=&#8221;yes&#8221; alignment=&#8221;center&#8221;][vc_column_text]<strong>What did Huida Gene like about the CoolLED pE-800?<\/strong><\/p>\n<ul>\n<li>Choice of eight wavelengths<\/li>\n<li>Fast switching speeds (&lt; 7 \u00b5s is possible using TTL)<\/li>\n<li>Impressive brightness and signal-to-noise for the 385 nm\/470 nm\/560 nm\/590 nm channels used<\/li>\n<li>The 740 nm LED is a very useful for imaging in the NIR<\/li>\n<\/ul>\n<blockquote><p>For more information about Huida Gene, please visit: <a href=\"http:\/\/www.huidagene.com\">http:\/\/www.huidagene.com<\/a><\/p>\n<p>To learn how the pE-800 Illumination System can helps advance your application, please see <a href=\"https:\/\/www.coolled.com\/products\/pe-800\">www.coolled.com\/products\/pe-800<\/a><\/p><\/blockquote>\n<p>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text]<\/p>\n<p>Based in Shanghai, Huida Gene is a biopharmaceutical organisation that develops and produces therapeutics such as gene replacement and gene editing for rare single-gene disorders and chronic diseases.<\/p>\n<p>In this application example, scientists used the <a href=\"https:\/\/www.coolled.com\/products\/pe-800\/\">CoolLED pE-800<\/a> on a Nikon ECLIPSE Ni-E microscope to scan tissue sections in order to determine the location of lesions. [&#8230;]<\/p>\n","protected":false},"author":3,"featured_media":0,"template":"","research_field":[32,487],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>8-Channel Microscopy Illumination for Developing Novel Gene Therapeutics - CoolLED<\/title>\n<meta name=\"description\" content=\"This application note explains how Huida Gene benefit from 8-Channel Microscopy Illumination for Developing Novel Gene Therapeutics\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.coolled.com\/technical-resources\/app-notes\/8-channel-microscopy-illumination-for-developing-novel-gene-therapeutics\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"8-Channel Microscopy Illumination for Developing Novel Gene Therapeutics - 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