CoolLED LED Illumination Systems & Oxford Instruments’ Andor Cameras
Delivering precision photon management from source to sensor
CoolLED and Oxford Instruments share a single design philosophy: give instrument builders the freedom to assemble exactly the optical pathway their customers need.
By combining our LED Illumination Systems with Oxford Instruments’ market‑leading Andor sCMOS and EMCCD cameras – and flexibility to integrate into software using SDK or other 3rd party software – OEMs can create imaging platforms that scale from everyday fluorescence to the most demanding live‑cell and super‑resolution workflows.
CoolLED LED Illumination Systems – the Amora Series
At the heart of CoolLED’s OEM offering lies our Amora Series, a modular platform that translates our proven laboratory products into fully customisable solutions for instrumentation builders. Amongst many other capabilities, Amora lets you specify:
- Spectral coverage from 340 – 850 nm with a range of LED Channels, which is suitable for a huge range of applications in both the Life Sciences as well as Industrial Inspection and Materials Science.
- Filter architecture that ranges from clear pass‑through to inline excitation filters supplied either by CoolLED or by you.
- Light delivery options, including industry‑standard liquid‑light‑guide coupling or direct‑fit opto‑mechanical adapters for maximum irradiance at the sample.
- Connectivity tailored to your control stack – USB or RS‑232 for serial commands, high‑speed TTL (< 20 µs) or analogue (0‑10 V, 0‑50 kHz) for deterministic synchronisation.
All Amora solutions are built in an ISO‑certified environment, shipped with the documentation you need for CE, FDA and other regulatory submissions.
Oxford Instruments Andor detection: turning every photon into data
From the back‑illuminated iXon Ultra EMCCD for single‑molecule sensitivity to the large‑field Sona-11 (32mm), ultra-fast CB2 24B and workhorse ZL41 family, Andor cameras deliver exceptionally low read noise and quantum efficiency up to 95 %.
Paired with the stability of LED illumination, users can shorten exposure times, reduce photobleaching and still retain quantitative accuracy, even in the most challenging live‑cell experiments.
Andor iXon EMCCD Cameras
iXon EMCCDs are the gold standard detectors of the biophysics laboratory. Refined and perfected for the most challenging low light applications, they offer a raw sensitivity unmatched by sCMOS based technology.
Andor sCMOS Cameras
Andor’s ZL41 Cell, CB2-24B and Sona scientific CMOS (sCMOS) cameras are optimised for high fidelity, quantitative scientific measurements.
A range of sensor formats cover most imaging applications with a combination of sensitivity, speed and resolution over wide fields of view.
C-RED SWIR/NIR II High Speed InGaAs Cameras
The C-Red series enables imaging into the (SWIR) NIR II band using InGaAs detector technologies. This enables deeper imaging into tissues of larger model organisms.
These products integrate easily with CoolLED Illumination Systems via standard TTL or USB commands.
Mosaic 3 & MicroPoint 4 photostimulation tools
DMD and high-speed galvo systems provide full control of illumination delivery for optogenetics, FRAP, ablation and other photoactivation applications. Can be integrated into most popular microscope systems.
Precision photostimulation with Mosaic
The Mosaic 3 digital‑mirror‑device delivers sub‑micron spatial control for optogenetics, photoactivation and FRAP. When driven by an Amora LED Illumination System, users gain:
- Up to 5 kHz frame‑by‑frame patterning with LED switching inside a 20 µs TTL window.
- Flexible wavelength selection, including UV for uncaging and far‑red for deep‑tissue stimulation.
- Long operational lifetime and low maintenance compared with arc or laser alternatives.
Targeted DNA damage and ablation with MicroPoint
The MicroPoint 4 is a highly effective tool for DNA damage, Ablation and FRAP studies. This laser-based system is fully compatible as part of a system using the Amora LED illumination systems.
- Precise and agile photostimulation with MicroPoint 4 lasers
Visualisation provided by the Amora LED system
Why OEM teams choose the CoolLED + Oxford Instruments’ Andor combination
| Integration challenge | Solution |
| Tight synchronisation of shutters, scanners and cameras | Sub‑millisecond TTL/analogue control shared by Amora and Fusion |
| Minimising thermal load on sensitive samples | Low‑heat LED output plus Andor deep‑cooled sensors |
| Rapid instrument customisation for niche applications | Modular Amora design and Andor’s extensible camera range |
| Regulatory and environmental compliance | Mercury‑free LEDs with CE/FDA documentation, backed by ISO manufacturing |
Move your design forward
Whether you are prototyping a compact benchtop imager or scaling up a flagship confocal, the compatibility between CoolLED LED Illumination Systems and Andor detection hardware takes risk out of your development timeline.
Contact us today to discuss wavelengths, mechanical interfaces or driver integration, and discover how straightforward advanced imaging can be.
